The
Biomaterials Group provides basic materials science, engineering,
test methods, and standards to sectors of the health care industry
for the development of new or improved materials and delivery systems
with a strong emphasis on tissue engineering and related technologies.
Whereas current medical implants are engineered to be biologically
inert, the goal of tissue engineering is to utilize our understanding
of tissue repair processes to design advanced medical devices that
promote regeneration
There
are currently tissue engineered medical products under development
for virtually every organ in the body. FDA-approved skin substitutes
have been available for the last 10 years, and great progress is being
made in regenerative cartilage, muscle, bone, and dental therapies.
One cornerstone of these therapies is biomaterials that serve as temporary
replacements for missing or damaged tissue but are also designed to
interact with native repair processes in order to facilitate the restoration
of function. The successful development and regulatory approval of
such biomaterials requires advanced measurement methods and reference
materials, and the Biomaterials Group is currently working in three
main areas toward providing such a metrology system:
Combinatorial methods for screening
cellular responses to biomaterials
New techniques for characterizing the
performance of tissue engineering scaffolds